Identification of lysolipid receptors involved in...

C - Chemistry – Metallurgy – 12 – N

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C12N 15/12 (2006.01) A61K 31/66 (2006.01) C07K 14/705 (2006.01) C12N 5/10 (2006.01) C12N 15/85 (2006.01) G01N 33/68 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2324972

A lysolipid receptor, a human EDG-4 receptor, a method of identifying lysolipid receptors involved in inflammatory response and the lysolipid receptors so identified, and a method of identifying ligands which interact with such lysolipid receptors.

La présente invention concerne un récepteur de lysolipides, un récepteur de l'EDG-4 humaine. L'invention concerne également, d'une part un procédé permettant d'identifier des récepteurs des lysolipides impliqués dans la réponse inflammatoire, et d'autre part les récepteurs de lysolipides ainsi identifiée. L'invention concerne enfin un procédé permettant d'identifier les ligands présentant des interactions avec de tels récepteurs de lysolipides.

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