Identification of neuroblastoma tumor suppressor genes

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/62 (2006.01) C07H 21/00 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) C07K 19/00 (2006.01) C12N 15/12 (2006.01) C12Q 1/68 (2006.01) G01N 33/574 (2006.01)

Patent

CA 2422099

The present invention relates to a new tumor suppressor gene family. More specifically the present invention relates to a tumor suppressor involved in suppression of neuroblastoma. Said tumor suppressor is involved in the generation of micronuclei and in the removal of acentric chromosomal fragments that might contain amplified DNA.

La présente invention concerne une nouvelle famille du gène suppresseur du neuroblastome. Elle concerne plus particulièrement un suppresseur de tumeur impliqué dans la suppression du neuroblastome. Le suppresseur de tumeur intervient dans la production de micronoyaux et dans l'élimination de fragments chromosomiques acentriques contenant éventuellement un ADN amplifié.

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