Identification of novel oligonucleotide drugs and reagents...

Details Identification of novel oligonucleotide drugs and reagents... Identification of novel oligonucleotide drugs and reagents...

C - Chemistry, Metallurgy

12

Q

C12Q 1/70 (2006.01) A61K 31/70 (2006.01) A61K 48/00 (2006.01) C07H 21/00 (2006.01) C12N 15/11 (2006.01) C12Q 1/02 (2006.01) C12Q 1/68 (2006.01) G01N 33/50 (2006.01)

Patent

CA 2081984

2081984 9117266 PCTABS00008 Methods for identifying oligonucleotides capable of hybridizing with nucleic acid of an infectious agent are disclosed. In accordance with preferred embodiments, oligonucleotides capable of antisense interaction with RNA which is significant to a bodily state of an animal or which is contributory to a diseased state is identified. Therapeutic, diagnostic and research methods and compositions employing such oligonucleotides are provided. Prior knowledge of the sequence of nucleic acid in the infectious agent is generally not required.

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