C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/68 (2006.01) C12Q 1/48 (2006.01) C40B 30/04 (2006.01)
Patent
CA 2700200
The invention provides the identification of oncogenic pathways activated in cytologically normal airway cells of individuals having or at risk of having lung disease, as well as specific gene expression patterns (biomarkers) associated with pathway activation. These biomarkers and pathways may provide prognostic and/or diagnostic indicators in lung disease, e.g., lung cancer. Additionally, these pathways and biomarkers may provide therapeutic targets for the treatment of lung disease, as well as markers for the assessment of treatment efficacy.
La présente invention concerne l'identification de voies oncogènes activées dans des cellules de voies aériennes cytologiquement normales d'individus ayant une maladie des poumons ou présentant le risque d'en avoir une, ainsi que des motifs d'expression de gène spécifiques (biomarqueurs) associés à l'activation des voies. Ces biomarqueurs et voies peuvent fournir des indicateurs de pronostic et/ou de diagnostic dans une maladie des poumons, par exemple un cancer des poumons. En outre, ces voies et biomarqueurs peuvent fournir des cibles thérapeutiques pour le traitement d'une maladie des poumons, ainsi que des marqueurs pour l'estimation de l'efficacité d'un traitement.
Bild Andrea
Brody Jerome S.
Gustafson Adam
Spira Avrum
Smart & Biggar
The Trustees Of Boston University
The University Of Utah Research Foundation
LandOfFree
Identification of novel pathways for drug development for... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Identification of novel pathways for drug development for..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Identification of novel pathways for drug development for... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1737117