Identification of novel substrate i-traf of ikk-i kinase

Details Identification of novel substrate i-traf of ikk-i kinase Identification of novel substrate i-traf of ikk-i kinase

C - Chemistry, Metallurgy

12

N

C12N 15/54 (2006.01) A61K 31/70 (2006.01) A61K 38/46 (2006.01) C12N 9/12 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2316836

Novel IB kinase IKK-i which is a novel serine/threonine kinase capable of activating a transcription factor NF-B which inhibits the expression of various genes relating to immune response; a gene encoding the same; and medicinal compositions containing the same.

L'invention concerne: une nouvelle I?B kinase, la kinase IKK-i, qui est une nouvelle sérine/thréonine kinase pouvant activer un facteur de transcription NF-?B qui inhibe l'expression de différents gènes associés à la réponse immunitaire; un gène codant pour cette kinase; et des compositions médicales contenant cette kinase.

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