C - Chemistry – Metallurgy – 40 – B
Patent
C - Chemistry, Metallurgy
40
B
C40B 40/02 (2006.01) C12Q 1/68 (2006.01) C40B 40/06 (2006.01) C40B 70/00 (2006.01)
Patent
CA 2752622
The present invention features methods and compositions for the identification of molecules that facilitate the intracellular delivery of a, e.g., nucleic acid molecule. The methods and compositions of the invention utilize any display methodology wherein a library (e.g., a small molecule or protein library) is coupled to a nucleic acid (e.g., RNA or DNA) that encodes each library member.
La présente invention concerne des procédés et des compositions permettant l'identification de molécules facilitant l'administration intracellulaire d'une molécule d'acide nucléique par exemple. Les procédés et compositions de l'invention font appel à une quelconque méthodologie d'affichage dans le cadre de laquelle une banque (par exemple une banque de petites molécules ou de protéines) est couplée à un acide nucléique (par exemple un ARN ou un ADN) codant pour chaque membre de ladite banque.
Chen Yan
Shamah Steven Mark
Wagner Richard W.
Borden Ladner Gervais Llp
X-Body Inc.
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