C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/68 (2006.01) C07K 14/47 (2006.01)
Patent
CA 2495252
The invention relates to the identification and selection of sequences which demonstrate particular advantage in identifying individuals having osteoarthritis (OA). The invention also provides a selection of sequences particularly useful in diagnosing the degree of advancement of osteoarthritis of an individual and in the identification of novel therapeutic targets for OA. The invention further provides for the use of these sequences as a tool to diagnose disease progression and to monitor the efficacy of therapeutic regimens.
L'invention concerne l'identification et la sélection de séquences présentant un avantage particulier pour identifier des individus atteints d'ostéo-arthrite (OA). L'invention fournit également une sélection de séquences particulièrement utiles pour diagnostiquer le degré d'avancement de l'ostéo-arthrite chez un individu ainsi que pour l'identification de nouvelles cibles thérapeutiques pour l'OA. L'invention concerne en outre l'utilisation de ces séquences en tant qu'outil pour diagnostiquer la progression de la maladie et pour contrôler l'efficacité des schémas thérapeutiques.
Liew Choong-Chin
Marshall Wayne K.
Zhang Hongwei
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Chondrogene Inc.
Genenews Corporation
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