A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 38/16 (2006.01) A61K 31/7088 (2006.01) A61K 39/04 (2006.01) A61K 39/40 (2006.01) A61P 31/04 (2006.01) C07K 14/35 (2006.01) C07K 16/12 (2006.01) C07K 19/00 (2006.01) C12N 15/31 (2006.01) C12N 15/62 (2006.01) G01N 33/569 (2006.01)
Patent
CA 2361246
The present invention relates to compositions useful in immunization against pathogenic organisms of the genus Mycobacterium and for diagnostic purposes. In particular, the present invention relates to a composition comprising at least one protein which is differentially expressed in a virulent strain as compared to an avirulent strain of Mycobacteria. Furthermore, the invention relates to compositions comprising fusion proteins, antigenic fragments, nucleic acid molecules encoding the aforementioned proteinaceous compounds and/or antibodies thereto. Additionally, the invention relates to pharmaceutical and diagnostic compositions comprising or employing compounds of the invention. In addition, the present invention relates to the use of the compounds of the invention for the treatment of Mycobacterium induced diseases and/or for the preparation of a vaccine for vaccination against Mycobacterium induced diseases.
L'invention concerne des compositions utilisées lors de l'immunisation contre des organismes pathogènes du genre Mycobacterium, et à des fins de diagnostic. Notamment, cette invention concerne une composition contenant au moins une protéine qui est exprimée différentiellement dans une souche virulente en comparaison à une souche virulente de Mycobacteria. En outre, ladite invention a trait à des compositions contenant des protéines de fusion, des fragments antigèniques, des molécules d'acides nucléiques codant les composés protéiniques susmentionnés et/ou les anticorps correspondants. Par ailleurs, l'invention concerne des compositions pharmaceutiques et diagnostiques contenant ou utilisant des composés de cette invention. De plus, ladite invention porte sur l'utilisation des composés de cette invention pour traiter des maladies causées par Mycobacterium et/ou pour préparer un vaccin destiné à la vaccination contre des maladies causées par Mycobacterium.
Jungblut Peter
Kaufmann Stefan H. E.
Lamer Stephanie
Mattow Jens
Mollenkopf Hans
Chiron Behring Gmbh & Co.
Goudreau Gage Dubuc
Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften E.v.
LandOfFree
Identification of specific differentially expressed... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Identification of specific differentially expressed..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Identification of specific differentially expressed... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1534286