Identification of tissue/cell specific marker genes and use...

C - Chemistry – Metallurgy – 12 – Q

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C12Q 1/68 (2006.01)

Patent

CA 2492504

A cartilage array comprises a plurality of different polynucleotide probe spots stably associated with a solid surface of a carrier, whereby each of said spots is made of a unique polynucleotide that corresponds to one specific cartilage marker gene. Said specific cartilage marker genes preferably are at least in part selected from a group of 467 genes that could be shown to be cartilage related.

Un réseau de cartilage comprend une pluralité de différents points de sonde de polynucléotide, associés de manière stable avec une surface solide d'un support, chacun desdits points étant formé d'un polynucléotide unique qui correspond à un gène marqueur de cartilage spécifique. Lesdits gènes marqueurs de cartilage spécifiques sont, de préférence, sélectionnés au moins partiellement, à partir d'un groupe de 467 gènes qui pourraient être considérés comme étant apparentés au cartilage.

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