C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 7/04 (2006.01) A61K 38/04 (2006.01) A61P 31/12 (2006.01) A61P 35/00 (2006.01)
Patent
CA 2656883
The present invention relates to the field of peptide immunotherapy. In particular, the invention pertains to a method for identifying a HLA-B*0702-restricted cryptic epitope in an antigen, and to a method for increasing its immunogenicity. The invention also provides novel methods and materials for efficiently treating patients having an HLA- B*0702 phenotype.
La présente invention concerne le domaine de l'immunothérapie peptidique. En particulier, l'invention concerne un procédé permettant d'identifier un épitope cryptique restreint à HLA-B*0702 dans un antigène, ainsi qu'un procédé permettant d'augmenter son immunogénicité. L'invention concerne également de nouveaux procédés et des matériaux permettant de traiter efficacement des patients présentant un phénotype HLA-B*0702.
Graff-Dubois Stephanie
Kosmatopoulos Kostantinos (kostas)
Menez-Jamet Jeanne
Robic
Vaxon Biotech
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