Identifying peptide ligands of target proteins with target...

C - Chemistry – Metallurgy – 12 – Q

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C12Q 1/68 (2006.01) A61K 38/02 (2006.01) A61K 39/395 (2006.01) C07K 16/28 (2006.01) C12P 19/34 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2350163

Methods and compositions are provided for identifying peptide ligands of target proteins with target complementary libraries. This technology allows the selection of complementary peptides of high binding affinity to the target proteins. Methods and compositions for identifying prophylactic and therapeutic peptides for allergy and the common cold are also provided.

L'invention concerne des méthodes et une composition d'identification de ligands peptidiques de protéines cibles avec des banques complémentaires de cibles. Cette technique permet la sélection de peptides complémentaires présentant une grande affinité de liaison pour les protéines cibles. L'invention concerne également des méthodes et des compositions d'identification de peptides prophylactiques et thérapeutiques contre les allergies et le rhume banal.

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