Ifi206, a novel interferon-induced polypeptide, and nucleic...

C - Chemistry – Metallurgy – 12 – N

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C12N 15/00 (2006.01) A01K 67/00 (2006.01) A01K 67/027 (2006.01) A61K 38/17 (2006.01) A61K 38/21 (2006.01) C07K 14/435 (2006.01) C07K 14/455 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) C07K 19/00 (2006.01) C12N 1/15 (2006.01) C12N 1/19 (2006.01) C12N 1/21 (2006.01) C12N 5/10 (2006.01) C12N 15/09 (2006.01) C12N 15/12 (2006.01) C12N 15/20 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2402877

The present invention provides novel mouse interferon-inducible proteins (IFI206 and naturally occuring variants) modulated under conditions that affect metabolic status and the polynucleotides that identify and encode IFI206. The invention provides for genetically engineered expression vectors and host cells comprising the nucleic acid sequence encoding IFI206 and for a method for producing the protein. The invention also provides pharmaceutical compositions containing IFI206 and the use of such compositions for the prevention or treatment of diseases associated with the expression of IFI206. Additionally, the invention provides antisense molecules to IFI206 and their use in the treatment of diseases associated with the expression of IFI206. The invention also provides diagnostic assays that utilize polynucleotides that hybridize with naturally occurring sequences encoding IFI206 and antibodies that specifically bind to the protein.

L'invention concerne de nouvelles protéines de la souris pouvant être induites par un interféron (IF1206 et leur variante naturelle) modulé dans des conditions jouant un rôle sur l'état métabolique, ainsi que les polynucléotides identifiant et codant IF1206. Elle concerne des vecteurs d'expression produits par génie génétique et des cellules hôtes contenant la séquence d'acide nucléique codant IFI206, et un procédé servant à préparer cette protéine. Elle concerne également des compositions pharmaceutiques contenant IFI206 et l'utilisation de ces compositions pour la prévention ou le traitement de maladies associées à l'expression de IFI206. Elle concerne, de plus, des molécules antisens par rapport à IFI206 et leur utilisation dans le traitement de maladies associées à l'expression de IFI206. Elle concerne également des méthodes diagnostiques mettant en application des polynucléotides s'hybridant aux séquences naturelles codant IFI206 et des anticorps se liant de façon spécifique à la protéine.

LandOfFree

Say what you really think

Search LandOfFree.com for Canadian inventors and patents. Rate them and share your experience with other people.

Rating

Ifi206, a novel interferon-induced polypeptide, and nucleic... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Ifi206, a novel interferon-induced polypeptide, and nucleic..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Ifi206, a novel interferon-induced polypeptide, and nucleic... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFCA-PAI-O-1744198

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.