Ifosfamide compositions for parenteral administration and a...

Details Ifosfamide compositions for parenteral administration and a... Ifosfamide compositions for parenteral administration and a...

A - Human Necessities

61

K

A61K 31/724 (2006.01) A61K 31/33 (2006.01)

Patent

CA 2507848

The present invention provides aqueous Ifosfamide compositions and a process for their preparation, in which the compositions have a reduced toxicity over and above the concomitant use of the uroprotective agent, Mesna. Aqueous compositions of Ifosfamide can be prepared at a concentration as high as 1100mg/ml.

La présente invention concerne des compositions aqueuses à base d'Ifosfamide et leur procédé de préparation. Ces compositions présentent une toxicité encore plus réduite que quand l'on utilise de façon concomitante l'agent uroprotecteur Mesna. On peut préparer des compositions à base d'Ifosfamide à une concentration aussi élevée que 1 100 mg/ml.

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