Ige antibody production inhibitors and autoimmune diseases...

A - Human Necessities – 61 – K

Patent

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A61K 31/505 (2006.01) A61K 31/44 (2006.01) A61K 31/506 (2006.01) A61K 31/513 (2006.01) C07D 213/72 (2006.01) C07D 239/46 (2006.01) C07D 239/47 (2006.01) C07D 413/12 (2006.01) C07K 5/078 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2323443

IgE antibody production inhibitors and autoimmune diseases inhibitors characterized by containing as the active ingredient heterocyclic amide compounds represented by general formula (1) or pharmacologically acceptable salts thereof, wherein R represents hydrogen, alkyl, -CHO, -COOH, etc.; R5, R6 and R7 represent each hydrogen, alkyl, aryl, etc.; M represents carbon or nitrogen; Y represents aryl, etc.; and Z represents hydrogen, alkyl, aryl, etc.

La présente invention porte sur des inhibiteurs de production d'anticorps IgE et sur des inhibiteurs de maladies auto-immunes qui se caractérisent en ce qu'ils contiennent en tant qu'ingrédient actif des composés amide hétérocycliques représentés par la formule (1) ou bien des sels pharmacologiquement acceptables de ces derniers. Dans la formule (1), R représente hydrogène, alkyle, -CHO, -COOH, etc.; R?5¿, R?6¿ et R?7¿ représentent chacun hydrogène, alkyle, aryle, etc.; M représente carbone ou azote; Y représente aryle, etc.; et Z représente hydrogène, alkyle, aryle, etc.

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