A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 47/48 (2006.01) C07K 16/00 (2006.01) C12N 15/87 (2006.01)
Patent
CA 2647768
This invention is directed to a approach for focusing and expressing DNA vaccinates in Antigen Presenting Cells (APCs) mediated through targeting IgE receptors (Fc&egr;Rs) on APC and driving DNA expression through provision of an APC specific regulatory element This vaccine can be used in the prevention or treatment of allergic disease.
Cette invention concerne une nouvelle technique pour concentrer et exprimer des vaccins à ADN dans des cellules présentant l'antigène (CPA) dont la diffusion est facilitée par le ciblage des récepteurs des IgE (Fc.epsilon.Rs) sur les APC et l'induction de l'expression d'ADN par la fourniture d'un élément de régulation spécifique aux APC. Ce vaccin peut être utilisé dans la prévention ou le traitement de la maladie allergique.
Saxon Andrew
Zhang Ke
Smart & Biggar
The Regents Of The University Of California
LandOfFree
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