Igf antagonist peptides

Details Igf antagonist peptides Igf antagonist peptides

C - Chemistry, Metallurgy

07

K

C07K 7/08 (2006.01) A61K 38/10 (2006.01) A61K 38/30 (2006.01) A61K 47/48 (2006.01) A61P 3/10 (2006.01) A61P 35/00 (2006.01) C07K 14/65 (2006.01) C07K 17/00 (2006.01) G01N 33/566 (2006.01) G01N 33/574 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2439735

Peptides are provided that antagonize the interaction of IGF-1 with its binding proteins, insulin receptor, and IGF receptor. These IGF antagonist peptides are useful in treating disorders involving IGF-1 as a causative agent, such as, for example, various cancers.

L'invention concerne des peptides qui antagonisent l'interaction d'IGF-1 avec ses protéines de liaison, le récepteur de l'insuline et le récepteur d'IGF. Ces peptides antagonistes d'IGF sont utiles pour le traitement de troubles impliquant l'IGF-1 comme agent responsable, tels que, par exemple, divers cancers.

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