Igm-mediated receptor clustering and cell modulation

Details Igm-mediated receptor clustering and cell modulation Igm-mediated receptor clustering and cell modulation

A - Human Necessities

61

K

A61K 39/395 (2006.01) C07K 14/47 (2006.01) C07K 16/28 (2006.01)

Patent

CA 2734173

Materials and methods for using multivalent molecules (e.g., antibodies) to modulate cellular function. A molecule can be targeted to a particular type of cell, either through direct binding to an epitope on the surface of the cell, or through a linker that recognizes both the multivalent molecule and a marker on the cell surface.

L'invention concerne des matériaux et des procédés destinés à utiliser des molécules multivalentes (p. ex. des anticorps) pour moduler la fonction cellulaire. Une molécule peut être ciblée sur un type de cellule particulier, soit par liaison directe à un épitope à la surface de la cellule, soit par un agent de liaison qui reconnaît à la fois la molécule multivalente et un marqueur à la surface de la cellule.

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