Il-1 inhibitors process for producing il-1 inhibitors and...

Details Il-1 inhibitors process for producing il-1 inhibitors and... Il-1 inhibitors process for producing il-1 inhibitors and...

C - Chemistry, Metallurgy

07

K

530/15.06, 195/1

C07K 14/435 (2006.01) A61K 38/17 (2006.01) C07K 14/47 (2006.01) C12N 15/09 (2006.01) A61K 38/00 (2006.01)

Patent

CA 1341026

This invention relates to interleukin 1 inhibitors (IL-1 INHs) that selectively inhibit interleukin 1 activity. The invention also relates to processes for purifying such IL-1 INHs from urine and for producing such IL-1 INHs by hosts transformed with recombinant DNA molecules comprising DNA sequences encoding the inhibitors, and to methods of treatment and compositions characterized by such IL-1 INHs. These methods and agents are useful in immunosuppressive and anti-inflammatory applications and therapies.

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