Il-1 receptor based antagonists and methods of making and using

Details Il-1 receptor based antagonists and methods of making and using Il-1 receptor based antagonists and methods of making and using

C - Chemistry, Metallurgy

12

N

C12N 15/62 (2006.01) C07K 14/715 (2006.01) C07K 19/00 (2006.01) C12P 21/02 (2006.01)

Patent

CA 2502385

The present invention provides a fusion polypeptide capable of binding interleukin -1 (IL-1) to form a nonfunctional complex. It also provides a nucleic acid sequence encoding the fusion polypeptide and methods of making and uses for the fusion polypeptide.

La présente invention concerne un polypeptide hybride capable de lier interleukine-1 (IL-1) de manière à former un complexe non fonctionnel. L'invention concerne également une séquence d'acides nucléiques codant le polypeptide hybride et des procédés de fabrication et d'utilisation dudit polypeptide hybride.

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