Il-10 related peptides for wound healing

Details Il-10 related peptides for wound healing Il-10 related peptides for wound healing

A - Human Necessities

61

K

A61K 38/20 (2006.01) A61P 17/02 (2006.01)

Patent

CA 2594798

The present invention relates to the use of a peptide, or derivative thereof of general formula Xl-X2-X3-ThT-X4-LyS-X5-ATg-X6 for promoting accelerated wound healing with reduced scarring. Xl is Ala or GIy; X2 is Tyr or Phe; X3, X4 and X5 are independently selected from the group comprising Met, He, Leu and VaI; and X6 is selected from the group comprising Asp, GIn and GIu. In a preferred embodiement, the peptide is Ala-Tyr-Met-Thr-Met-Lys-Ile-Arg-Asn or AYMTMKIRN .

La présente invention concerne l'utilisation d'un peptide ou de l'un de ses dérivés représenté par la formule générale X1-X2-X3-ThT-X4-LyS-X5-ATg-X6 pour favoriser la guérison accélérée des blessures avec une moindre formation des cicatrices. Dans cette formule, X1 est Ala ou Giy. X2 est Tyr ou Phe. X3, X4 et X5 sont indépendamment choisis dans le groupe comprenant Met, He, Leu et VaI. Enfin, X6 est choisi dans le groupe comprenant Asp, GIn et Glu.

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