Il-12 immunotherapy for cancer

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/867 (2006.01) A61K 38/20 (2006.01) A61K 39/00 (2006.01) A61K 48/00 (2006.01) A61P 35/00 (2006.01) A61P 35/02 (2006.01) A61P 37/04 (2006.01) C07K 14/54 (2006.01) C12N 5/10 (2006.01) C12N 15/24 (2006.01) C12P 21/02 (2006.01)

Patent

CA 2723320

Compositions and methods for delivering immune modulatory molecules to result in a therapeutic effect are disclosed. The compositions and methods use stably integrating lentiviral delivery systems. The methods are useful for therapeutically and prophylactically treating cancer such as leukemia.

L'invention concerne des compositions et des méthodes d'administration de molécules modulatrices immunes en vue d'obtenir un effet thérapeutique. La composition et les méthodes de cette invention utilisent des systèmes d'administration de vecteur lentiviraux à intégration stable. Ces méthodes sont utiles dans le traitement thérapeutique et prophylactique du cancer tel que la leucémie.

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