Il-13 receptor specific chimeric proteins and uses thereof

Details Il-13 receptor specific chimeric proteins and uses thereof Il-13 receptor specific chimeric proteins and uses thereof

C - Chemistry, Metallurgy

12

N

C12N 15/62 (2006.01) A61K 38/20 (2006.01) A61K 47/48 (2006.01) A61K 49/00 (2006.01) A61K 51/08 (2006.01) C07K 14/21 (2006.01) C07K 14/54 (2006.01) C07K 16/28 (2006.01) C07K 19/00 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2215122

The present invention provides a method and compositions for specifically delivering an effector molecule to a tumor cell. The method involves providing a chimeric molecule that comprises an effector molecule attached to a targeting molecule that specifically binds an IL-13 receptor and contacting a tumor cell with the chimeric molecule.

L'invention a pour objet un procédé et des compositions pour administrer une molécule effectrice à une cellule tumorale. Ce procédé consiste à fournir une molécule chimère qui comprend une molécule effectrice fixée à une molécule cible qui se lie, de manière spécifique, au récepteur IL-13 et à amener une cellule tumorale en contact avec la molécule chimère.

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