Il-17 antagonistic antibodies for treating cancer

Details Il-17 antagonistic antibodies for treating cancer Il-17 antagonistic antibodies for treating cancer

C - Chemistry, Metallurgy

07

K

C07K 16/24 (2006.01)

Patent

CA 2637166

An IL-17 binding molecule, in particular an antibody to human IL-17, more preferably a human antibody to human IL-17 is provided, wherein the hypervariable regions of the heavy and light chains have amino acid sequences as defined, for use in the treatment of a solid or hematological malignant diseases.

La présente invention concerne une molécule de liaison à IL-17, en particulier un anticorps dirigé contre l'IL-17 humaine, mieux encore un anticorps humain dirigé contre l'IL-17 humaine, les régions hypervariables des chaînes lourdes et légères comportant des séquences d'acides aminés telles que définies. La molécule est utilisée dans le traitement de maladies malignes solides ou hématologiques.

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