A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 38/20 (2006.01) A61K 38/18 (2006.01) A61K 38/19 (2006.01) A61K 38/21 (2006.01) A61K 38/30 (2006.01) A61P 17/02 (2006.01)
Patent
CA 2669109
IL-17B is known to stimulate the proliferation of chondrocytes, bone, and is highly expressed in nervous tissue, resulting in repair of diseased tissue. When IL-17B is absent a marked negative effect on wound healing is noted. The present invention comprises providing IL-17B, by topical, parental, or other administration means, in order to accelerate the wound healing process. The present invention further encompasses a pharmaceutical composition and formulations thereof that utilize IL-17B, either alone or in combination with other cytokines or growth factors known to aid wound healing. The invention also contemplates methods of treating wounds in patients using this pharmaceutical composition.
L'IL-17B est connu pour stimuler la prolifération des chondrocytes, d'os, et pour son expression élevée dans le tissu nerveux, entraînant la réparation de tissu malade. Lorsque l'IL-17B est absent, on observe un effet nettement négatif sur la cicatrisation. La présente invention concerne la fourniture de l'IL-17B, par administration topique, parentérale, ou d'autres moyens, afin d'accélérer le processus de cicatrisation. L'invention concerne également une composition pharmaceutique et leurs formulations mettant en AEuvre l'IL-17B, seul ou en combinaison avec d'autres cytokines ou facteurs de croissance connus pour leur aide à la cicatrisation. L'invention concerne en outre des procédés de traitement de plaies chez des patients mettant en AEuvre cette composition pharmaceutique.
Haugen Harald S.
Moore Emma E.
Osler Hoskin & Harcourt Llp
Zymogenetics Inc.
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