Il-21 receptor antagonists

Details Il-21 receptor antagonists Il-21 receptor antagonists

C - Chemistry, Metallurgy

07

K

C07K 16/28 (2006.01) A61K 39/395 (2006.01)

Patent

CA 2632218

Monoclonal antibodies to the IL-21 receptor and multimeric complexes comprising the IL-21 receptor; including monoclonal antibodies to the heterodimeric receptor, IL-21/IL-2R ; have been prepared. The invention also describes a method of producing said antibodies. And, the invention also describes a method of treatment comprising using said antibodies to suppress an immune response.

La présente invention concerne des anticorps monoclonaux préparés contre le récepteur de IL-21 et contre des complexes multimères comprenant le récepteur de IL-21, y compris des anticorps monoclonaux anti-récepteur hétérodimére de IL-21/IL-2R. L'invention concerne également un procédé de production desdits anticorps ainsi qu'un procédé de traitement qui utilise lesdits anticorps pour supprimer une réponse immunitaire.

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