Il-2r-associated polypeptide and dna molecules coding therefor

C - Chemistry – Metallurgy – 12 – N

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Details

C12N 15/12 (2006.01) A61K 31/711 (2006.01) A61K 38/17 (2006.01) C07H 21/04 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) C12P 21/02 (2006.01)

Patent

CA 2209858

The present invention relates to a polypeptide, p43, which is associated with the interleukin-2 receptor (IL-2R). It binds specifically to the .beta. and .gamma. subunits of IL-2R and is further capable of binding NAD+. The invention is further related to nucleic acid molecules coding for p43 and to antibodies specifically binding p43.

La présente invention se rapporte à un polypeptide, le p43, lequel est associé au récepteur de l'interleukine-2 (IL-2R), se lie spécifiquement aux sous-unités beta et gamma de IL-2R et est en outre capable de fixer NAD<+>. L'invention se rapporte encore à des molécules d'acide nucléique codant pour p43 ainsi qu'aux anticorps fixant spécifiquement p43.

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