C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 14/435 (2006.01) A61K 38/17 (2006.01)
Patent
CA 2743394
The present invention relates to small peptides derived from a cytokine, interleukin-4 (IL-4), capable of binding to the IL-4 receptors and inhibiting macrophage activation, and thereby preventing the onset of inflammatory response. The inven-tion further relates to use of said peptides for the production of a medicament for the treatment of different pathological condi-tions, wherein IL-4 plays a prominent role.
La présente invention concerne de petits peptides dérivés dune cytokine, linterleukine-4 (IL-4), capables de se lier aux récepteurs dIL-4 et dinhiber lactivation des macrophages, et prévenir ainsi lapparition dune réponse inflammatoire. Linvention concerne en outre lutilisation desdits peptides pour la production dun médicament pour le traitement de différentes affections pathologiques, dans lesquelles IL-4 joue un rôle prédominant.
Berezin Vladimir
Bock Elisabeth
Koebenhavns Universitet
Norton Rose Canada S.e.n.c.r.l.,s.r.l./llp
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