Il-7 variants with reduced immunogenicity

Details Il-7 variants with reduced immunogenicity Il-7 variants with reduced immunogenicity

C - Chemistry, Metallurgy

07

K

C07K 14/54 (2006.01) C07K 16/46 (2006.01) A61P 31/18 (2006.01) A61P 35/00 (2006.01) C12N 15/24 (2006.01)

Patent

CA 2591297

The invention relates generally to IL-7 molecules modified to reduce their immunogenicity. These molecules include also fusion proteins comprising said modified IL-7 molecules and immunoglobulin molecules or portions thereof.

L'invention concerne, d'une manière générale, des molécules de l'IL-7 modifiées aux fins de réduction de l'immunogénicité de celles-ci. Ces molécules comprennent également des protéines hybrides renfermant les molécules de l'IL-7 modifiées et des molécules de l'immunoglobuline ou des parties de celles-ci.

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