Il10 snp associated with acute rejection

C - Chemistry – Metallurgy – 12 – Q

Patent

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C12Q 1/68 (2006.01)

Patent

CA 2611361

The present invention concerns a method for the prediction of acute renal transplant rejection by detecting a polymorphism in the promoter region of the IL 10 gene, optionally in combination with polymorphisms of the MDRl and IMPDH2 genes which were found to be associated with this disease.

La présente invention concerne une méthode de prédiction d'un rejet violent de transplantation rénale par détection d'un polymorphisme dans la région du promoteur du gène IL 10, facultativement, en combinaison avec des polymorphismes des gènes MDRl et IMPDH2 qui sont associés à cette maladie.

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