Image averaging for angiography by registration and...

A - Human Necessities – 61 – B

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358/11

A61B 6/00 (2006.01) G03B 41/16 (1980.01)

Patent

CA 1138575

Docket No. 1920-123 Inventors: Samuel H. Brooks, Robert H. Selzer Donald W. Crawford and David H. Blankenhorn Title: IMAGE AVERAGING FOR ANGIOGRAPHY BY REGISTRATION AND COMBINATION OF SERIAL IMAGES ABSTRACT OF THE DISCLOSURE A method and apparatus for angiography in which information contained within multiple serial images of contrast medium flowing through a blood vessel is combined to form a single image having improved vessel edge delineation. More specifically, a method is disclosed whereby a contrast medium opaque to X-rays is injected into a blood vessel distant from an artery section of interest, preferably injected into a vein, whereby the contrast medium is mixed with blood prior to its passing through the artery section. Multiple X-ray images are obtained as the contrast medium and blood mixture flows through the artery section. These multiple images are registered with respect to each other according to a landmark contained within the patient, the landmark having a predetermined relationship to the vessel of interest. The landmark could be a bone, catheter or any other material opaque to X-rays. Density measurements are made with respect to each corresponding image segment or element of the multiple images and are combined to synthesize a composite image. The synthesized image has an edge un- certainty equal to that of one of the individual images divided by the square root of the total number of images utilized.

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