Imaging agents of fibrotic diseases

A - Human Necessities – 61 – K

Patent

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Details

A61K 49/00 (2006.01) C08G 69/48 (2006.01) A61B 6/00 (2006.01) C08G 69/10 (2006.01)

Patent

CA 2736368

Agents and methods for imaging a cell and/or a portion of tissue characterized by fibrosis, as well as to agents and methods for determining and/or diagnosing fibrotic diseases are disclosed herein. Also disclosed herein are polymer conjugates that can include a detectable label, a retinoid and a polymer. The polymer conjugates can be used to image a portion of tissue, deliver a detectable label to a portion of tissue or a cell and/or diagnosis a condition or disease.

La présente invention concerne des agents et des procédés dimagerie dune cellule et/ou dune partie de tissu caractérisé par la fibrose, ainsi que des agents et des procédés permettant de déterminer et/ou de diagnostiquer des maladies fibrotiques. La présente invention concerne également des conjugués polymères qui peuvent inclure un traceur détectable, un rétinoïde et un polymère. Ces conjugués polymères peuvent être utilisés pour réaliser limagerie dune partie de tissue, fournir un traceur détectable à une partie de tissu ou une cellule, et/ou diagnostiquer un état ou une maladie.

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