Imaging and therapeutic agents targeting proteins expressed...

Details Imaging and therapeutic agents targeting proteins expressed... Imaging and therapeutic agents targeting proteins expressed...

A - Human Necessities

61

K

A61K 51/08 (2006.01) A61K 51/10 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2572453

Methods of delivering an agent in a tissue-specific manner, by targeting proteins expressed on endothelial cell surface, are described. The methods can be used for detecting, imaging and/or treating neoplasia, angiogenesis or neovasculature, as well as for diagnostics and methods of assessing treatment efficacy.

Des procédés d'administration d'un agent d'une manière spécifique au tissu par ciblage des protéines exprimées sur la surface d'une cellule endothéliale. Les procédés peuvent servir à détecter, imager et/ou traiter une tumeur, une angiogenèse ou une néovascularisation, ainsi qu'à diagnostique et mettre en oeuvre des procédés d'évaluation de l'efficacité d'un traitement.

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