G - Physics
01
N
G01N 21/47 (2006.01) G01N 21/25 (2006.01) G01N 21/64 (2006.01)
Patent
CA 2508846
An imaging device (46) comprises a carrier stage (12a) for carrying a sample slide (14a) including a micro-array of cellular binding event samples, a linear light source (37a) for illuminating the sample slide (14a), and a motor drive (16a) for moving the carrier stage (12a) relative to the sample slide (14a) such that successive portions of the sample slide (14a) are illuminated by the light source (37a). A digital opitical line scan camera system (44a) is disposed such that, in use, it captures substantially only the successive portions of light rays (40a) which emerge from the sample slide at an offset angle relative to light rays (42a) from light source transmitted through and emerging from the sample slide (14a) to generate a series of linear dark field images arranged to be reconstructed into a composite image of the sample slide or array of samples.
L'invention porte sur un dispositif d'imagerie (46) comprenant: une plate-forme (12a) recevant une microplaquette (14a) portant des microréseaux d'échantillons d'événements de liaison de cellules; une source linéaire de lumière (37a) éclairant la microplaquette (14a); un entraînement (16) déplaçant la plate-forme (12a) par rapport à la microplaquette (14a) pour en éclairer successivement toutes les parties; et une caméra numérique à balayage linéaire (44a) disposée de manière à ne capturer quasiment que les rayons lumineux (40a) émergeant de la microplaquette (14a) en faisant un angle donné par rapport aux rayons incidents (42a) de manière à produire une série d'images sur fond noir pouvant être reconstituées en image composite des microplaquettes ou des réseaux d'échantillons.
Alexander John
Chandler Michael Bruce
Medsaic Pty Ltd
Smart & Biggar
LandOfFree
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