Imaging infection using fluorescent protein as a marker

Details Imaging infection using fluorescent protein as a marker Imaging infection using fluorescent protein as a marker

C - Chemistry, Metallurgy

12

N

C12N 1/21 (2006.01) A61K 35/66 (2006.01) A61K 49/00 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2452876

A method to follow the progress of infection in vertebrate subjects utilizes infective agents which have been modified to express a fluorescent protein. The method can also monitor expression of genes associated with infective agents during the course of infection. The method may further include targeting tumors with the modified infective agents.

La présente invention concerne un procédé permettant de suivre la progression d'une infection dans des sujets vertébrés utilisant des agents infectieux qui ont été modifiés pour exprimer une protéine fluorescente. Le procédé peut également suivre l'expression des gènes associés aux agents infectieux en cours d'infection. Le procédé peut en outre inclure le ciblage des tumeurs avec les agents infectieux modifiés.

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