Imaging probes

Details Imaging probes Imaging probes

C - Chemistry, Metallurgy

12

Q

C12Q 1/37 (2006.01) A61K 49/00 (2006.01) C07K 5/00 (2006.01) C07K 5/02 (2006.01) C07K 5/08 (2006.01) C07K 5/10 (2006.01) G01N 33/573 (2006.01)

Patent

CA 2678717

The present invention relates to molecular probes of the formula (I) {L1 -R1 -L}n-A-CO-NH-R2-L2 (I) as defined herein that allow for the observation of the catalytic activity of a selected cathepsin in in vitro assays, in cells or in multicellular organisms, a method for their preparation and the use thereof.

Sondes moléculaires de formule (I) {L1 -R1 -L}n-A-CO-NH-R2-L2 (I) telle que définie ici permettant l'observation de l'activité catalytique d'une cathepsine sélectionnée dans des dosages in vitro, dans des cellules ou des organismes multicellulaires; procédé associé à leur élaboration; et utilisation de celles-ci.

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