Imaging the dopamine transporter to determine ad-hd

A - Human Necessities – 61 – B

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A61B 5/00 (2006.01) A61K 51/04 (2006.01)

Patent

CA 2375968

A method of diagnosing attention deficient-hyperactivity disorder (AD-HD) in a human patient by assessing dopamine transporter in at least one region of the patient's central nervous system, where an elevated level of dopamine transporter in the patient is indicative of AD-HD. In embodiments of the invention, assessment of dopamine transporter levels includes assessing binding of a dopamine transporter ligand to dopamine transporter using PET or SPECT.

L'invention concerne une méthode permettant de diagnostiquer le trouble de déficit d'attention avec hyperactivité (TDAH) chez un patient, en évaluant la présence de transporteurs de dopamine dans au moins une région du sytème nerveux central du patient, un niveau élevé de transporteurs de dopamine indiquant la présence de TDAH. Dans certains modes de réalisation de la présente invention, l'évaluation des niveaux de transporteurs de dopamine consiste à lier un ligand du transporteur de dopamine à un transporteur de dopamine au moyen de l'imagerie TEP ou SPECT.

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