Imidate prodrugs of pharmaceutically useful anticonvulsant...

C - Chemistry – Metallurgy – 07 – H

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C07H 13/00 (2006.01) A61K 31/70 (2006.01) C07H 9/04 (2006.01) C07H 11/00 (2006.01)

Patent

CA 2098076

Imidate derivatives of sulfamates having the following formula (I): (see formula I) wherein R1, R2, R3, R4 and X are as herein defined have been found to be useful prodrug and exhibit anticonvulsant activity when converted to the active agent upon administration to a mammal and are thus useful in the treatment of conditions such as epilepsy. Further, the present invention encompasses pharmaceutical compositions containing a compound of formula (I) as well as methods for their use.

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