Imidazo¬1,2-a|pyrazines

C - Chemistry – Metallurgy – 07 – D

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C07D 487/04 (2006.01) C07D 213/73 (2006.01) C07D 471/04 (2006.01) C07F 9/6561 (2006.01)

Patent

CA 1202630

A B S T R A C T The invention relates to imidazo[l,2-a]pyrazines of the general formula Image (wherein the substituents R2,R3,R4 and R5 are as defined in the specification) and includes 2,3-dihydro-, 5,6,7,8- tetrahydro-, 2,3,5,6,7,8-hexahydro-analogues and salts of such compounds. The invention also relates to processes for preparing such compounds and to phacmaceutical compo- sitions containing them. The compounds are antisecretory and cytoprotective agents and are particularly useful in the treatment of ulcer diseases.

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