Imidazo¬1,2-a|pyrazines for the treatment of neurological...

Details Imidazo¬1,2-a|pyrazines for the treatment of neurological... Imidazo¬1,2-a|pyrazines for the treatment of neurological...

C - Chemistry, Metallurgy

07

D

C07D 487/04 (2006.01) A61K 31/4985 (2006.01) A61P 25/22 (2006.01) A61P 25/24 (2006.01) C07D 235/00 (2006.01) C07D 241/00 (2006.01)

Patent

CA 2419626

Provided herein are imidazo[1,2-a]pyrazines of the formula (I) as well as compositions, including pharmaceutical compositions, containing the same, and the use thereof in the treatment of various neurological and psychological disorders, e.g., anxiety and depression, treatable by antagonizing CRF receptors.

L'invention concerne des imidazo[1,2-a]pyrazines correspondant à la formule (I), de même que des compositions, notamment des compositions pharmaceutiques, contenant ces composés, ainsi que l'utilisation de celles-ci dans le traitement de diverses affections neurologiques et psychologiques, par exemple l'angoisse et la dépression, que l'on peut traiter en antagonisant les récepteurs de la substance libératrice de la corticotropine.

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