Imidazo[1,2-a]pyridine derivatives

Details Imidazo[1,2-a]pyridine derivatives Imidazo[1,2-a]pyridine derivatives

C - Chemistry, Metallurgy

07

D

C07D 471/14 (2006.01) A61K 31/437 (2006.01) A61K 31/4375 (2006.01) A61K 31/496 (2006.01) A61K 31/5377 (2006.01) A61K 31/541 (2006.01) A61P 31/00 (2006.01) A61P 31/10 (2006.01) C07D 471/04 (2006.01) C07D 493/14 (2006.01) C07D 495/14 (2006.01)

Patent

CA 2474850

A compound represented by the following formula (I), which has antifungal activity in a wide spectrum by a novel mechanism, i.e., 1,6-.szlig.-glucan synthesis inhibition, and can specifically or selectively exhibit such activity, a salt thereof, or a solvate of either; and an antifungal agent containing any of these.

L'invention concerne un composé représenté par la formule (I) suivante:, possédant une activité antifongique de large spectre mettant en jeu un nouveau mécanisme, c'est à dire, une inhibition de la synthèse de 1,6-.beta.-glucane, et qui peut montrer spécifiquement ou sélectivement une telle activité. L'invention concerne aussi un sel ou un solvate de ce composé, ou une combinaison des deux, ainsi qu'un agent antifongique contenant l'un de ces composés.

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