Imidazo[1.2-a]quinoline derivatives, their preparation and...

C - Chemistry – Metallurgy – 07 – D

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260/246.1, 260/2

C07D 471/04 (2006.01)

Patent

CA 1263389

ABSTRACT IMIDAZO[1.2-a]QUINOLINE DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM Compounds which are imidazo[1.2-a]quinoline derivatives of general formula (I) Image (I) in which X is hydrogen, halogen, methyl, methoxy, methylthio or methylsulphonyl, Y is hydrogen, halogen or methyl in position 6, 7 or 8, and R1 and R2, which may be the same or different, each is hydrogen, methyl or ethyl, or R1 and R2 together form a tetramethylene, pentamethylene, 3-methyl-3- azapentamethylene, 3-ethoxycarbonyl-3-azapentamethylene or 3-oxapentamethylene group, and their pharmacologically acceptable acid addition salts have anxiolytic, sleep-inducing, hypnotic and anticonvulsant properties.

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