Imidazo [1,2-b] pyridazine compounds as modulators of liver...

Details Imidazo [1,2-b] pyridazine compounds as modulators of liver... Imidazo [1,2-b] pyridazine compounds as modulators of liver...

C - Chemistry, Metallurgy

07

D

C07D 487/04 (2006.01) A61K 31/5025 (2006.01) A61P 3/00 (2006.01) A61P 9/00 (2006.01)

Patent

CA 2710458

This invention relates generally to imidazo[1,2-b] pyridazine-based modulators of Liver X receptors (LXRs) having formula (I) and related methods: Formula (I) wherein R2 is C6-C10 aryl or heteroaryl including 5-10 atoms, each of which is: (i) substituted with 1 R6, and (ii) optionally substituted with from 1-5 R e; and R1, R3, R4, R5, R6 and R e are defined herein.

La présente invention concerne de manière générale des modulateurs des récepteurs X du foie (LXR) à base d'imidazo-[1,2-b]-pyridazine de formule (I) et des procédés en relation avec ceux-ci : Formule (I) R2 étant un aryle ou hétéroaryle en C6 à C10 comprenant 5 à 10 atomes, chacun d'entre eux étant : (i) substitué par un R6, et (ii) éventuellement substitué par de 1 à 5 Re ; et R1, R3, R4, R5, R6 et Re étant tels que définis ici.

Affiliated with

Also associated with

Rating

Imidazo [1,2-b] pyridazine compounds as modulators of liver... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Imidazo [1,2-b] pyridazine compounds as modulators of liver..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Imidazo [1,2-b] pyridazine compounds as modulators of liver... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1387038