Imidazo (1,2-.beta.) isoquinoline derivatives

Details Imidazo (1,2-.beta.) isoquinoline derivatives Imidazo (1,2-.beta.) isoquinoline derivatives

C - Chemistry, Metallurgy

07

D

260/271.3

C07D 471/04 (2006.01) C07C 45/46 (2006.01) C07C 45/63 (2006.01) C07C 49/813 (2006.01) C07D 271/10 (2006.01)

Patent

CA 1069123

ABSTRACT 5,10-Dihydro-imidazo(1,2b)isoquinolines substituted in the 2- and/or 3-position(s) by an aromatic group have analgesic, anti- inflammatory or anti-pyretic activity. Except for 2-phenyl-5,10- dihydroimidazo(1,2b)isoquinoline, they are believed to be novel compounds. They can be prepared in manner known per se by heating a 2-acylmethyl isoquinolinium salt with an ammonium salt of an organic acid or by reaction of a 3-amino-1, 4-dihydroisoquinoline with an x-halogenocarbonyl compound.

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