Imidazo 1,5a pyridine derived serine protease inhibitors

Details Imidazo 1,5a pyridine derived serine protease inhibitors Imidazo 1,5a pyridine derived serine protease inhibitors

C - Chemistry, Metallurgy

07

D

C07D 471/04 (2006.01) A61K 31/435 (2006.01) A61K 31/55 (2006.01) A61K 38/05 (2006.01) A61K 38/06 (2006.01) C07K 5/02 (2006.01) C07K 5/06 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2222960

The invention relates to an imidazo[1,5a]pyridine derived serine protease inhibitor comprising a unit having general formula (I) wherein R1 is hydrogen, lower alkyl or an acyl group; R2 is hydrogen or lower alkyl; R3 and R4 are independently hydrogen, lower alkyl or together form =CH-NR5R6, R5 and R6 being lower alkyl. The compounds are serine protease inhibitors and can be used for the treatment and prophylaxis of thrombosis and thrombin-associated diseases.

Cette invention concerne un inhibiteur de sérine protéase dérivé de imidazo[1,5a]pyridine, lequel inhibiteur comprend une unité correspondant à la formule générale (I) où R¿1? représente hydrogène, alkyle inférieur ou un groupe acyle; R¿2? représente hydrogène ou alkyle inférieur; R¿3? et R¿4? représentent indépendamment hydrogène, alkyle inférieur ou forment ensemble =CH-NR¿5?R¿6?, R¿5? et R¿6? représentant un alkyle inférieur. Ces composés sont des inhibiteurs de sérine protéase et peuvent être utilisés dans le traitement et la prévention de thromboses et de maladies associées à la thrombine.

Affiliated with

Also associated with

Rating

Imidazo 1,5a pyridine derived serine protease inhibitors does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Imidazo 1,5a pyridine derived serine protease inhibitors, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Imidazo 1,5a pyridine derived serine protease inhibitors will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1559346