C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 513/04 (2006.01) A61K 31/41 (2006.01) A61P 3/00 (2006.01) A61P 7/00 (2006.01) A61P 21/00 (2006.01) A61P 25/00 (2006.01) A61P 27/00 (2006.01) A61P 39/00 (2006.01)
Patent
CA 2617532
Provided herein are novel sirtuin-modulating compounds and methods of use thereof. The sirtuin-modulating compounds may be used for increasing the lifespan of a cell, and treating and/or preventing a wide variety of diseases and disorders including, for example, diseases or disorders related to aging or stress, diabetes, obesity, neurodegenerative diseases, cardiovascular disease, blood clotting disorders, inflammation, cancer, and/or flushing as well as diseases or disorders that would benfit from increased mitochondrial activity. Also provided are compositions comprising a sirtuin-modulating compound in combination with another therapeutic agent.
La présente invention se rapporte à de nouveaux composés modulant la sirtuine et leurs procédés d~utilisation. Les composés modulant la sirtuine peuvent être utilisés pour accroître la durée de vie d~une cellule, et traiter et/ou prévenir une grande variété de maladies et de troubles comprenant, par exemple, des maladies ou des troubles liés au vieillissement ou au stress, au diabète, à l~obésité, aux maladies neurodégénérescentes, à une maladie cardiovasculaire, aux troubles de la coagulation sanguine, à l~inflammation, au cancer et/ou aux bouffées vasomotrices ainsi que des maladies ou des troubles qui tireraient avantage d~une activité mitochondriale accrue. L~invention se rapporte également à des compositions comprenant modulant la sirtuine en combinaison avec un autre agent thérapeutique.
Bemis Jean
Disch Jeremy S.
Milne Jill
Ng Pui Yee
Nunes Joseph J.
Borden Ladner Gervais Llp
Sirtris Pharmaceuticals Inc.
LandOfFree
Imidazo [2,1-b] thiazole derivatives as sirtuin modulating... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Imidazo [2,1-b] thiazole derivatives as sirtuin modulating..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Imidazo [2,1-b] thiazole derivatives as sirtuin modulating... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1399688