Imidazo [4,5-b] pyridine derivatives used as raf inhibitors

Details Imidazo [4,5-b] pyridine derivatives used as raf inhibitors Imidazo [4,5-b] pyridine derivatives used as raf inhibitors

C - Chemistry, Metallurgy

07

D

C07D 471/04 (2006.01) A61K 31/437 (2006.01) A61P 13/12 (2006.01) A61P 35/00 (2006.01) C07C 311/08 (2006.01)

Patent

CA 2716947

Compounds of Formula I are useful for inhibition of Raf kinases. Methods of using compounds of Formula I and stereoisomers and pharmaceutically acceptable salts thereof, for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions are disclosed.

L'invention porte sur des composés de formule I qui sont utiles pour l'inhibition des kinases Raf. L'invention porte également sur des procédés d'utilisation de composés de Formule I et des stéréo-isomères et sels pharmaceutiquement acceptables de ceux-ci, pour un diagnostic in vitro, in situ et in vivo, la prévention ou le traitement de tels troubles dans des cellules de mammifères, ou d'états pathologiques associés.

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