Imidazo [4,5-.beta.] pyridine compounds and process for...

C - Chemistry – Metallurgy – 07 – D

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C07D 471/04 (2006.01) A61K 31/395 (2006.01) A61K 31/435 (2006.01) A61K 31/44 (2006.01) C07D 231/54 (2006.01)

Patent

CA 1329204

IMIDAZO [4,5-b] PYRIDINE COMPOUNDS AND PROCESS FOR PREPARING SAME ABSTRACT OF THE DISCLOSURE Imidazo[4,5-b]pyridine compounds of the general formula [I] are provided: Image [I] where R1 is straight-chain or branched C1-8 alkoxy which may be substituted with cycloalkyl, or C2-4 fluoro- alkyloxy, R2 is H, methyl or methoxy, and R3 and R4 are each H or methyl and may be the same or different. All these compounds have good activity of inhibiting potassium ion-dependent adenosine triphosphatase and excellent storage stability, so that they are usable for the treatment of gastric and/or duodenal ulcers.

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