C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 487/04 (2006.01) A61K 31/55 (2006.01)
Patent
CA 2346542
The subject invention involves compounds having the structure: (1) wherein the C.alpha.-N.beta., C5-C6, and C6-C7 bonds a re each single or double bonds, except that both C5-C6 and C6-C7 are double bonds; R1 is selected from hydrogen, alkyl, aryl, and heterocycle; R2 - R15 are independently selected from hydrogen and other substituents; and pharmaceutically-acceptable forms thereof. The subject invention also involves pharmaceutical compositions containing such compounds, and methods for treating or preventing diseases and disorders using such compounds.
L'invention porte sur des composés de structure: (1) dans laquelle les liaisons C¿.alpha.?-N¿.beta.?, C¿5?-C¿6?, et C¿6?-C¿7? sont simples ou doubles, sauf C¿5?-C¿6? et C¿6?-C¿7? qui sont des liaisons doubles; R1 est choisi parmi hydrogène, alkyle, aryle et un hétérocycle; R2-R15 sont choisis indépendamment entre hydrogène et d'autres substituants; et sur leurs formes pharmacocompatibles. L'invention porte également sur des compositions pharmaceutiques contenant lesdits composés et sur des procédés de traitement et de prévention de maladies et troubles à l'aide desdits composés.
Liu Song
Pong Schwe Fang
Portlock David Edward
Kirby Eades Gale Baker
The Procter & Gamble Company
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