C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 471/14 (2006.01) A61K 31/519 (2006.01) A61P 11/00 (2006.01) A61P 25/00 (2006.01) A61P 29/00 (2006.01) C07D 221/00 (2006.01) C07D 235/00 (2006.01) C07D 239/00 (2006.01) C07D 487/14 (2006.01)
Patent
CA 2479644
The present invention discloses compounds corresponding to formula (I): wherein A, Z, Z1, Y, R1 and R2 are as defined in the specification, as well as pharmaceutical formulations, methods of making and uses thereof for the treatment of p38 mediated diseases.
Cette invention concerne les composés représentés par la formule (I) dans laquelle A, Z, Z?1¿, Y, R?1¿ et R?2¿ sont tels que définis dans la description, ainsi que des formulations pharmaceutiques, des méthodes de préparation et d'utilisation de celles-ci pour le traitement de maladies induites par la p38.
Goldstein David Michael
Hawley Ronald Charles
Lui Alfred Sui-Ting
Sjogren Eric Brian
Borden Ladner Gervais Llp
F. Hoffmann-La Roche Ag
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