Imidazo-triazine derivatives as pde 5 inhibitors

Details Imidazo-triazine derivatives as pde 5 inhibitors Imidazo-triazine derivatives as pde 5 inhibitors

C - Chemistry, Metallurgy

07

D

C07D 487/04 (2006.01) A61K 31/53 (2006.01) A61P 15/10 (2006.01)

Patent

CA 2442329

Compounds of general formula (1): wherein R1, R2, R3, R4, X, Y and A have the meanings given herein which are useful in the curative and prophylactic treatment of a medical condition for which inhibition of a cyclic guanosine 3', 5'- monophosphate phosphodiesterase (e.g. cGMP PDE5) is desired.

Cette invention concerne des composés représentés par la formule générale (1) dans laquelle R?1¿, R?2¿, R?3¿, R?4¿, X, Y et A sont comme définis dans le descriptif. Ces composés conviennent bien pour le traitement curatif et prophylactique d'un état pathologique pour lequel il est souhaitable d'inhiber une phosphodiestérase de guanosine 3', 5' monophosphatée cyclique (telle que cGMP PDE5).

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